Mar 25

A Guide to Amyloid-Related Imaging (ARIA) Abnormalities in Alzheimer's Disease Webinar

Please note: Interested learners that want to register will NEED TO CREATE AN ACCOUNT on the EfficientCME website.



  1. Recognize which medications/treatments that may be administered in the Emergency Department (ED) are inappropriate or contraindicated in patients prescribed amyloid-targeting therapies (ATTs) and strategize management protocols for clinical scenarios in which they would be utilized.
  2. Describe the range of symptoms of ARIA that may prompt a patient to seek emergency care and how to differentiate them from more common conditions to appropriately triage these individuals and determine next steps in their management.
  3. Isolate possible types of ARIA (ARIA-E, ARIA-H) as well as which do and do not require hospital admission/immediate treatment (e.g., corticosteroids) to effectively coordinate variable patient presentations.
  4.  Identify key areas of interdisciplinary communication that may impact a care team’s ability to successfully triage, diagnose, and/ or treat ARIA and employ corresponding solutions to maximize workflow efficiency and patient outcomes.


With the first approvals of ATTs for patients with early Alzheimer’s disease (AD) neurobiology, the way this illness is viewed and managed is facing a paradigm shift. However, while disease-modifying therapies (DMTs) are a long-awaited breakthrough in the treatment of AD, ATTs have also introduced new, class specific adverse effects, ARIA, with which most clinicians, regardless of specialty, have not yet come into contact, creating a host of novel considerations and potential practice changes. This lack of exposure and limited published guidance may be particularly problematic in ED settings which are likely to encounter the most urgent needs of those affected by ARIA.

This live virtual webinar focuses on emergency medicine clinicians’ role in the recognition and acute management of ARIA, including how ARIA may present and what courses of action are needed for different ARIA severities.

Moderated By

Don Melady


Dr. Don Melady is an emergency physician at Mount Sinai Hospital in Toronto, Canada and a founding member of the Geriatric Emergency Department Collaborative. He is the author of the website – a CME accredited program for geriatric emergency medicine education – and the chair of the Geriatric EM committee of the International Federation of Emergency Medicine.

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